Custom Enzymes and Inhibitors
Selleck Chemical LLC Lamivudine 10mg 134678-17-4 GR109714X
Lamivudine (GR109714X) is a potent nucleoside analog reverse transcriptase inhibitor, used for treatment of chronic HBV and HIV/AIDS. It works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Roscovitine (Seliciclib) 10mg 186692-46-6 CYC202
Roscovitine (Seliciclib, CYC202) is a potent and selective CDK inhibitor for Cdc2, CDK2 and CDK5 with IC50 of 0.65 ?M, 0.7 ?M and 0.16 ?M in cell-free assays. It shows little effect on CDK4/6. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Sb-612111 hydrochloride | 371980-98-2 | 99.3% | 454.86 | C24H30Cl3NO | 10 MG
SB-612111 hydrochloride is the hydrochloride salt of a selective NOP/ORL-1 receptor antagonist intended for preclinical research. Supplied as a solid with formulation and storage guidance, it is suitable for in vitro pharmacology and in vivo studies when prepared according to published protocols.
- High purity (99.3%), suitable for research applications.
- Hydrochloride salt form; chemical formula C24H30Cl3NO; molecular weight 454.86.
- Readily soluble in DMSO (≈15.62 mg/mL) with established in vivo formulation options.
- Supplied as a 10 mg solid, white to off-white in appearance.
- Recommended storage: powder -20 °C (3 years) or 4 °C (2 years); in solvent -80 °C (6 months).
Selleck Chemical LLC PD98059 10mM/1mL 167869-21-8
PD98059 is a non-ATP competitive MEK inhibitor with IC50 of 2 ?M in a cell-free assay, specifically inhibits MEK-1-mediated activation of MAPK; does not directly inhibit ERK1 or ERK2. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR) and functions as an AHR antagonist. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC TWS119 10mg 601514-19-6
TWS119 is a GSK-3? inhibitor with IC50 of 30 nM in a cell-free assay; capable of inducing neuronal differentiation and may be useful to stem cell biology. GSK-3? inhibition triggers autophagy. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Lm11a-31 dihydrochloride | 1243259-19-9 | MFCD13245016 | 99.9% | 316.27 g/mol | C12H27Cl2N3O2 | 5 MG
LM11A-31 dihydrochloride is a brain-penetrant, small-molecule modulator of the p75 neurotrophin receptor that acts as a potent proNGF antagonist. It is supplied for research use and has been reported to reverse cholinergic neurite dystrophy in Alzheimer's disease models.
- Brain-penetrant small molecule p75NTR modulator and proNGF antagonist.
- Reported to reverse cholinergic neurite dystrophy in Alzheimer's disease models.
- High purity (99.93%).
- Soluble in DMSO and water at up to 100 mg/mL; compatible with PBS for in vivo formulations.
- Available in small research sizes (for example, 5 mg) and larger quantities on request.
- Recommended storage: 4°C short-term; in solvent, -80°C up to 6 months and -20°C up to 1 month under inert atmosphere.
Selleck Chemical LLC Ondansetron HCl 10mg 99614-01-4 GR 38032F
Ondansetron HCl (GR 38032F) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation therapy. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Apexbio Technology LLC DBeQ, 177355-84-9, MFCD03691820, 10 mg
MF: C22H20N4, MW: 340.42, Solubility: 16mg/mL in DMSO. DBeQ is a selective and reversible inhibitor of p97 ATPase (IC50 = 1.5 uM) which induces caspase-3 and caspase-7 rapidly.
Apexbio Technology LLC Esomeprazole Sodium, 10mg. Cas: 161796-78-7 MFCD: MFCD07802816. Proton pump inhibitor
Esomeprazole sodium (Nexium) is the S-isomer of omeprazole and acts as a proton pump inhibitor. 161796-78-7. MFCD07802816
Ubpbio UB ALDEHYDE, 50UG
Ubiquitin Derivatives – Ubiquitin Aldehyde (UBPBio catalog# F3100) – Ub aldehyde is a potent and highly specific inhibitor of cysteine deubiquitinating enzymes including the Ub C-terminal hydrolases (UCHs), the Ub-specific proteases (USPs), the ovarian tumor domains (OTUs) proteases and the Machado-Josephine domain (MJD) proteases. Typical working concentration is 2-5 µM in vitro.
Selleck Chemical LLC Raltitrexed 10mg 112887-68-0 ZD-1694
Raltitrexed (ZD-1694) is a thymidylate synthase inhibitor with an IC50 of 9 nM for the inhibition of L1210 cell growth. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Biotang Inc BIIB021, CNF2024, Free Base, > 99%, 25MG, M.W. 318.76, C14H15ClN6O, CAS#848695-25-0
BIIB021, CNF2024, Free Base, > 99%, 25MG, M.W. 318.76, C14H15ClN6O, CAS#848695-25-0